New trials are underway for a drug called Betahistine. A recent pilot study of 20 volunteers showed a weight loss of almost 4lbs per week for three months. That’s as much as a 16 pound (~7kg) loss in a month.The drug has apparently been around for some years – and is used as a treatment for vertigo.
The drug works on a part of brain known as a histamine receptor, sending signals to the stomach, telling it to take in less food. It also seems to create a dislike of fatty foods. (Telegraph)
The new research will include double-blinded, placebo-controlled dose-ranging study in about 280 subjects over a period of three months (across the U.S) – via Betahistine.