Contrave: A New Miracle Weight Loss Pill?
Drug companies know that a pot of gold is up for grabs if they can only develop a break-through weight loss drug.
It looks like Contrave, one such contender, is one step closer to getting approval from the FDA which will open the drug up for sale in the USA.
At the end of a 56 week treatment study 48.2% of participants lost at least 10% of their body weight.
If you haven't heard about Contrave, it is a blend of two well known drugs;
- Wellbutrin - A drug used to treat depression.
- Naltrexone- A drug used to treat alcoholism and addiction.
What's more impressive is that 23% lost at least 15% of their body weight and 61.8% lost at least 5%. Only 23.1% lost 5% of their body weight on the placebo. Not only did the trial show impressive results concerning weight loss, but it also showed improvement in the participants' cholesterol and blood sugar levels.
Contrave is supposed to work differently than other weight loss drugs because it is believed to focus on the central nervous system to inhibit appetite, increase metabolism, reduce cravings, and to off set the body's natural defense of slowing down weight loss in order to preserve itself.
With such promising results and combining drugs that have been in use for 20 years, Contrave just could be the next big thing in weight loss. I guess time will tell if Contrave delivers that miracle or falls short in helping people conquer obesity.
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Hmmmmmm, what are the side effects & will we learn 20 years later that it was useless or caused some cancer....
ReplyIts a combination of two well known and well documented drugs that have already been used for some time.
ReplyHohum...another case of pharma companies making a drug cocktail because the patents on the individual components are going to expire soon. I've heard of doctors using Wellbutrin to aid weight loss and help depression, but I've never heard of Bupropion being used for anything besides to help smokers quit. I guess it could be a slight aid to people trying to lose weight, especially if they have addictive personalities, but it's probably mostly a placebo effect.
ReplyWithout actually being able to see the study (does anyone actually link to DATA anymore???) ... it sounds like they did account for placebo effects Spectra.
But, once again, it's focussing on fixing the 'disease' at the end - not on preventation. Even if this drug does work - and even if it doesn't have any deleterious side effects (a big if in my opinion) - it will only ever be a bandaid solution at best. Either people are going to have to change their eating and exercise habits or treatments like this will fail in terms of producing adults with long term sustainable healthy weights - unless they are meant to stay on the drug for their entire lives.
Reply"With such promising results and combining drugs that have been in use for 20 years, Contrave just could be the next big thing in weight loss. I guess time will tell if Contrave delivers that miracle or falls short in helping people conquer obesity."
Yeah...OK. BTW, who sponsored that study?
You forgot a third option. Several years ago, fenfluramine and phentermine which were drugs that were in use for decades were also combined and marketed as a weight-loss pill. We all know what happened with that nice little cocktail.
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