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Healthy Diet and Exercise Lowers Alzheimer's Risk

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A study of 1,800 people in their seventies, undertaken by Columbia University, found that diet and exercise are both factors in preventing the development of Alzheimer's, whether alone or in combination.

This is believed to be the first study where diet and exercise have been considered as separate factors in reducing the chances of developing Alzheimer's.

The research, led by Dr. Nikolaos Scarmeas, was published in the Journal of the American Medical Association (JAMA). None of the participants suffered from Alzheimer's at the start of the study, but after an average of 5 years, 282 cases of Alzheimer's were diagnosed (out of 1,800 study participants).

The data indicated that:

  • The people following the healthiest diets were 40% less likely to develop Alzheimer's than those with the worst diets

  • Those getting the most exercise were 37% less likely to develop Alzheimer's than those who didn't exercise at all

  • People in the top third for both diet and exercise were 59% less likely to develop Alzheimer's than those in the lowest third

A "healthy" diet was defined by the researchers as a "Mediterranean-type diet", ranked on a scale of 0-9. Both the duration and the intensity of exercise were also taken into account.

The New York Times explained that:

Diet may be protective because it can improve metabolic factors and reduce cardiovascular risks, inflammation and oxidative stress, [Dr Scarmeas] suggested, while physical activity has been associated with positive changes in the brain along with other positive effects.

With previous studies indicating that staying a healthy weight in middle age could cut Alzheimer's risk, this study adds to evidence that maintaining a healthy lifestyle throughout middle age and senior years can be a strong factor in preventing the development of Alzheimer's.

More like this in Science · Aug 27, 2009
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2 Comments

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Spectra on 08/27/09

Yet another reason to maintain a healthy diet and lifestyle for me. My grandpa (not the one who had severe heart disease) developed Alzheimer's and eventually passed away due to it, but he wasn't overweight. However, "healthy lifestyle" would have been about the furthest thing from describing his...he drank heavily for 40 years (he never admitted his alcoholism, but that's basically what he was), smoked two packs a day for 50 years, and lived on ham hocks, white bread, hot dogs, and pork rinds for most of his life.

Now I'm starting to notice early signs of dementia in my mom (my mom's dad was the grandpa that had Alzheimer's) and I'm concerned...she's constantly forgetting just about everything. I'll remind her that I'm coming to visit her a couple of days ahead of time and then when I'm on my way there, she forgets that I was planning to come. She confuses people's names all the time (she calls my brother in law the wrong name all the time and confuses my nephew's name with one of her dogs). She's overweight, but otherwise follows a fairly healthy diet. I really hope her problems are just part of getting old and not the beginning signs of Alzheimer's.

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kitekrazy on 08/30/09

I've had a lot of family die in their late 80's or are still alive and never had this. They weren't fit and trim either.

The thing they all had in common is that they read a lot.

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